Ulrich M Zanger: search on Z-Library

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1

MOLECULAR MECHANISMS OF GENETIC POLYMORPHISMS OF DRUG METABOLISM

Meyer, Urs A., Zanger, Ulrich M.

Journal:

Annual Review of Pharmacology

Year:

1997

Language:

english

File:

PDF, 213 KB

english, 1997

2

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Drug-Metabolizing Enzymes-An Overview

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 158 KB

english, 2012

3

Omics and Drug Response

Meyer, Urs A., Zanger, Ulrich M., Schwab, Matthias

Journal:

Annual Review of Pharmacology

Year:

2013

Language:

english

File:

PDF, 830 KB

english, 2013

4

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Zanger, Ulrich M., Schwab, Matthias

Journal:

Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

5

Polymorphic CYP2B6 : molecular mechanisms and emerging clinical significance

Zanger, Ulrich M, Klein, Kathrin, Saussele, Tanja, Blievernicht, Julia, H Hofmann, Marco, Schwab, Matthias

Journal:

Pharmacogenomics

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

6

Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels

Tremmel, Roman, Herrmann, Kristin, Engst, Wolfram, Meinl, Walter, Klein, Kathrin, Glatt, Hansruedi, Zanger, Ulrich M.

Journal:

Archives of Toxicology

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

7

The azole fungicide tebuconazole affects human CYP1A1 and CYP1A2 expression by an aryl hydrocarbon receptor-dependent pathway

Knebel, Constanze, Heise, Tanja, Zanger, Ulrich M., Lampen, Alfonso, Marx-Stoelting, Philip, Braeuning, Albert

Journal:

Food and Chemical Toxicology

Year:

2019

Language:

english

File:

PDF, 1.97 MB

english, 2019

8

RNA-Interference Approach to Study Functions of NADPH : Cytochrome P450 Oxidoreductase in Human Hepatocytes

Diana M. Feidt, Kathrin Klein, Andreas Nüssler, Ulrich M. Zanger

Journal:

Chemistry & Biodiversity

Year:

2009

Language:

english

File:

PDF, 614 KB

english, 2009

9

Patients with type ii autoimmune hepatitis express functionally intact cytochrome P-450 db1 that is inhibited by LKM-1 autoantibodies in vitro but not in vivo

Michael Manns, Ulrich Zanger, Guido Gerken, Kevin F. Sullivan, Karl-H. Meyer Zum Büschenfelde, Urs A. Meyer, Michel Eichelbaum

Journal:

Year:

1990

Language:

english

File:

PDF, 608 KB

english, 1990

10

Sex is a major determinant of CYP3A4 expression in human liver

Renzo Wolbold, Kathrin Klein, Oliver Burk, Andreas K. Nüssler, Peter Neuhaus, Michel Eichelbaum, Matthias Schwab, Ulrich M. Zanger

Journal:

Year:

2003

Language:

english

File:

PDF, 1.19 MB

english, 2003

11

Interindividual variability of canalicular ATP-binding-cassette (ABC)–transporter expression in human liver

Yvonne Meier, Christiane Pauli-Magnus, Ulrich M. Zanger, Kathrin Klein, Elke Schaeffeler, Andreas K. Nussler, Natascha Nussler, Michel Eichelbaum, Peter J. Meier, Bruno Stieger

Journal:

Year:

2006

Language:

english

File:

PDF, 993 KB

english, 2006

12

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

Anne T. Nies, Hermann Koepsell, Stefan Winter, Oliver Burk, Kathrin Klein, Reinhold Kerb, Ulrich M. Zanger, Dietrich Keppler, Matthias Schwab, Elke Schaeffeler

Journal:

Year:

2009

Language:

english

File:

PDF, 3.18 MB

english, 2009

13

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-rime PCR

Elke Schaeffeler, Matthias Schwab, Michel Eichelbaum, Ulrich M. Zanger

Journal:

Year:

2003

Language:

english

File:

PDF, 338 KB

english, 2003

14

6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4

Daniel Janke, Sherif Mehralivand, Dennis Strand, Ute Gödtel-Armbrust, Alice Habermeier, Ulrike Gradhand, Christine Fischer, Mohammad R. Toliat, Peter Fritz, Ulrich M. Zanger, Matthias Schwab, Martin F

Journal:

Year:

2008

Language:

english

File:

PDF, 362 KB

english, 2008

15

Three novel thiopurine S-methyltransferase allelic variants (TPMT20, 21, *22) – association with decreased enzyme function

Elke Schaeffeler, Michel Eichelbaum, Walter Reinisch, Ulrich M. Zanger, Matthias Schwab

Journal:

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

16

Discriminative Quantification of Cytochrome P4502D6 and 2D7/8 Pseudogene Expression by TaqMan Real-Time Reverse Transcriptase Polymerase Chain Reaction

Karin Endrizzi, Joachim Fischer, Kathrin Klein, Matthias Schwab, Andreas Nüssler, Peter Neuhaus, Michel Eichelbaum, Ulrich M. Zanger

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 176 KB

english, 2002

17

Limited Association of the 2988g>a Single Nucleotide Polymorphism with CYP2D641 in Black Subjects: Reply

Zanger, Ulrich M., Schwab, Matthias, Toscano, Claudia, Eichelbaum, Michel, Raimundo, Sebastian

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 53 KB

english, 2005

18

Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography–tandem mass spectrometry

Ute Hofmann, Matthias Schwab, Sonja Seefried, Claudia Marx, Ulrich M. Zanger, Michel Eichelbaum, Thomas E. Mürdter

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 288 KB

english, 2003

19

The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine

Birgit Eiermann, Georg Engel, Inger Johansson, Ulrich M. Zanger, Leif Bertilsson

Journal:

British Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 411 KB

english, 1997

20

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver

Janet K. Coller, Niels Krebsfaenger, Kathrin Klein, Karin Endrizzi, Renzo Wolbold, Thomas Lang, Andreas Nüssler, Peter Neuhaus, Ulrich M. Zanger, Michel Eichelbaum, Thomas E. Mürdter

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 146 KB

english, 2002

21

Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity

Janet K. Coller, Niels Krebsfaenger, Kathrin Klein, Renzo Wolbold, Andreas Nüssler, Peter Neuhaus, Ulrich M. Zanger, Michel Eichelbaum, Thomas E. Mürdter

Journal:

British Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 138 KB

english, 2004

22

A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes

Joachim Bucher, Stephan Riedmaier, Anke Schnabel, Katrin Marcus, Gabriele Vacun, Thomas S Weiss, Wolfgang E Thasler, Andreas K Nüssler, Ulrich M Zanger, Matthias Reuss

Journal:

BMC Systems Biology

Year:

2011

Language:

english

File:

PDF, 662 KB

english, 2011

23

Mass spectrometry-based absolute quantification of microsomal cytochrome P450 2D6 in human liver

Elmar Langenfeld, Ulrich M. Zanger, Klaus Jung, Helmut E. Meyer, Katrin Marcus

Journal:

Year:

2009

Language:

english

File:

PDF, 440 KB

english, 2009

24

New aspects on mechanisms of chemical carcinogenesis: emphasis on species and gender/sex differences and developmental/aging determinants

Franz Oesch, Cornelia Dietrich, Hanspeter Naegeli, Michael Schwarz, Gijsbertus van der Horst, Ulrich Zanger, Barbara Oesch, Carsten Weiss

Journal:

Archives of Toxicology

Year:

2008

Language:

english

File:

PDF, 226 KB

english, 2008

25

Limited contribution of CYP3A5 to the hepatic 6β-hydroxylation of testosterone

Landry K. Kamdem, Ingolf Meineke, Ina Koch, Ulrich M. Zanger, Jürgen Brockmöller, Leszek Wojnowski

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

26

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Ulrich M. Zanger, Miia Turpeinen, Kathrin Klein, Matthias Schwab

Journal:

Analytical and Bioanalytical Chemistry

Year:

2008

Language:

english

File:

PDF, 334 KB

english, 2008

27

Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene

Ricardo Bellott, Valérie Le Morvan, Virginie Charasson, Armelle Laurand, Marthe Colotte, Ulrich M. Zanger, Kathrin Klein, Denis Smith, Jacques Bonnet, Jacques Robert

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 291 KB

english, 2008

28

Non-synonymous polymorphisms in the humanSLCO1B1gene: an in vitro analysis of SNP

Annick Seithel, Kathrin Klein, Ulrich M. Zanger, Martin F. Fromm, Jörg König

Journal:

Molecular Genetics and Genomics

Year:

2008

Language:

english

File:

PDF, 454 KB

english, 2008

29

Age-dependent effect of plasma nitric oxide on parasite density in Ghanaian children with severe malaria

Jakob P. Cramer, Andreas K. Nüssler, Stephan Ehrhardt, Jana Burkhardt, Rowland N. Otchwemah, Philipp Zanger, Ekkehart Dietz, Sabine Gellert, Ulrich Bienzle, Frank P. Mockenhaupt

Journal:

Tropical Medicine & International Health

Year:

2005

Language:

english

File:

PDF, 180 KB

english, 2005

30

The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro

Eugen Muschler, Jawahar Lal, Alexander Jetter, Anke Rattay, Ulrich Zanger, Gregor Zadoyan, Uwe Fuhr, Julia Kirchheiner

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2009

Language:

english

File:

PDF, 207 KB

english, 2009

31

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

Gonzalez, Frank J., Skodat, Radek C., Kimura, Shioko, Umeno, Morio, Zanger, Ulrich M., Nebert, Daniel W., Gelboin, Harry V., Hardwick, James P., Meyer, Urs A.

Journal:

Year:

1988

File:

PDF, 530 KB

1988

32

Immunohistochemical Detection of Microsomal Epoxide Hydrolase in Human Synovial Tissue

Janne T. Backman, Isabel Siegle, Ulrich M. Zanger, Peter Fritz

Journal:

Journal of Molecular Histology

Year:

1999

Language:

english

File:

PDF, 131 KB

english, 1999

33

Distribution of Microsomal Epoxide Hydrolase in Humans: An Immunohistochemical Study in Normal Tissues, and Benign and Malignant Tumours

Janet K. Coller, Peter Fritz, Ulrich M. Zanger, Isabel Siegle, Michel Eichelbaum, Heyo K. Kroemer, Thomas E. Mürdter

Journal:

Journal of Molecular Histology

Year:

2001

Language:

english

File:

PDF, 2.32 MB

english, 2001

34

Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: Consequences for enzyme expression and busulfan conjugation*

Bredschneider, Monika, Klein, Kathrin, Mürdter, Thomas E., Marx, Claudia, Eichelbaum, Michel, Nüssler, Andreas K., Neuhaus, Peter, Zanger, Ulrich M., Schwab, Matthias

Journal:

Clinical Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

35

GSTP1andMDR1Genotypes and Central Nervous System Relapse in Childhood Acute Lymphoblastic Leukemia

Martin Stanulla, Elke Schäffeler, Stefan Arens, Anke Rathmann, André Schrauder, Karl Welte, Michel Eichelbaum, Ulrich M. Zanger, Martin Schrappe, Matthias Schwab

Journal:

International Journal of Hematology

Year:

2005

Language:

english

File:

PDF, 101 KB

english, 2005

36

Inhibition of human CYP2B6 by N,N′,N″-triethylenethiophosphoramide is irreversible and mechanism-based

Tanja Richter, Matthias Schwab, Michel Eichelbaum, Ulrich M. Zanger

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

37

Effect of CYP2B66 and CYP2C192 genotype on chlorpyrifos metabolism

Alice L. Crane, Kathrin Klein, Ulrich M. Zanger, James R. Olson

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

38

Identification of the human cytochromes P450 involved in the oxidative metabolism of “Ecstasy”-related designer drugs

Klaus-Peter Kreth, Karl-Artur Kovar, Matthias Schwab, Ulrich M Zanger

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 466 KB

english, 2000

39

Expression of intestinal drug-metabolizing enzymes in patients with chronic inflammatory bowel disease

Ulrich Klotz, Harald Hoensch, Tatjana Schütz, Philippe Beaune, Ulrich Zanger, Johann C. Bode, Peter Fritz

Journal:

Current Therapeutic Research

Year:

1998

Language:

english

File:

PDF, 586 KB

english, 1998

40

Frequency of C3435T polymorphism of MDR1 gene in African people

Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, Matthias Schwab

Journal:

Year:

2001

Language:

english

File:

PDF, 62 KB

english, 2001

41

Cytochrome P450 2B6: function, genetics, and clinical relevance

Turpeinen, Miia, Zanger, Ulrich M.

Journal:

Drug Metabolism and Drug Interactions

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

42

The genetic polymorphism of debrisoquine/sparteine metabolism—molecular mechanisms

Urs A. Meyer, Radek C. Skoda, Ulrich M. Zanger

Journal:

Pharmacology & Therapeutics

Year:

1990

Language:

english

File:

PDF, 1.34 MB

english, 1990

43

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Transporting Systems

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 160 KB

english, 2012

44

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Glutathione S-Transferases

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

45

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Hydrolytic Enzymes

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 285 KB

english, 2012

46

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Sulfotransferases

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 332 KB

english, 2012

47

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Importance of Pharmacogenomics

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 147 KB

english, 2012

48

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Introduction to Drug Metabolism

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 134 KB

english, 2012

49

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Cytochromes P450

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 298 KB

english, 2012

50

Metabolism of Drugs and Other Xenobiotics (ANZENBACHER:XENOBIOTICS O-BK) || Central Nervous System Drugs

Anzenbacher, Pavel, Zanger, Ulrich M.

Year:

2012

Language:

english

File:

PDF, 191 KB

english, 2012